Cognate rna-binding modes by the alternative-splicing regulator mbnl1 inferred from molecular dynamics

HIGHLIGHTS

• who: u00c0lex L. Gonzu00e1lez and collaborators from the , Barcelona, Spain have published the paper: Cognate RNA-Binding Modes by the Alternative-Splicing Regulator MBNL1 Inferred from Molecular Dynamics, in the Journal: (JOURNAL)
• what: Particularly, MBNL1 has been the main focus of intense studies over the past years due to its implication in the Myotonic Dystrophy (DM) pathogenic pathway . The authors address these questions using a combination of molecular dynamics (MD) simulations and bioinformatic analyses. The authors characterized the motions of the four zinc-fingers present in MBNL1 and provided a complementary picture to the experimental . . .
  

   

  

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