Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator

HIGHLIGHTS

• What: The authors show that at an alternative upstream promoter of is controlled in part by a locus (QTL). By altering levels the authors demonstrate that this in turn controls the expression of the isoforms. at this region is also sensitive to folate levels as the authors have previously shown in this cohort. The FASSTT Offspring Trial was conducted to investigate the effects of maternal folic acid (FA) administration on the cognitive development of children, and these were followed up at 3 years, 7 years and 11 years of age . The current analysis investigates a subgroup of . . .
  

   

  

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