Cohesin-mediated loop anchors confine the locations of human replication origins

HIGHLIGHTS

  • who: Daniel J. Emerson from the Institute of Mental Health grants ( R , and DP , have published the research: Cohesin-mediated loop anchors confine the locations of human replication origins, in the Journal: (JOURNAL) of 31/Dec/2020
  • what: On the basis of the observations , the authors reason that a failure of cohesin to unload, and therefore the creation of new long-range loops due to more cohesin molecules stalled at complex CTCF boundaries in G1 phase, might result in an increased number of high-efficiency origins or a narrowing of their genomic placement in S . . .

     

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