Cohesin releases dna through asymmetric atpase-driven ring opening

HIGHLIGHTS

  • who: Ahmed M.O. Elbatsh from the Netherlands Cancer Institute, Plesmanlaan, CX Amsterdam, The Netherlands University of have published the article: Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening, in the Journal: (JOURNAL) of February/18,/2016
  • what: The authors propose that Smc3 acetylation locks cohesin rings around the sister chromatids by counteracting an activity associated with one of cohesin's two
  • how: Hereby the authors identified an unexpected asymmetric activity within the heart of cohesin's ATPase machinery that drives DNA release from cohesin rings. The authors chose this system as . . .

     

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