Cohort profile: biomarkers related to folate- dependent one- carbon metabolism in colorectal cancer recurrence and survival – the focus consortium

HIGHLIGHTS

  • who: Cohort profile and collaborators from the with a history of CRC or (partial) bowel resection, chronic inflammatory bowel disease, or a known hereditary CRC syndrome are excluded from the studyPatients are recruited from , regional and academic hospitals prior to surgery. Individuals donate blood samples and provide information on diet, lifestyle and dietary supplement use at CRC diagnosis, that is, baseline, and at, (chemotherapy patients only), and , months after diagnosis. Clinical data are collected through review of medical records (treatment-u00adinduced toxicity) or through linkage with the Dutch ColoRectal Audit (DCRA). Mortality data (ie, death or alive . . .

     

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