Col10a1-ddr2 axis promotes the progression of pancreatic cancer by regulating mek/erk signal transduction

HIGHLIGHTS

  • who: Zhihui Wen from the Royal North Shore Hospital, Australia Nanchang University, China have published the research work: COL10A1-DDR2 axis promotes the progression of pancreatic cancer by regulating MEK/ERK signal transduction, in the Journal: (JOURNAL)
  • how: The GEPIA dataset showed that COL10A1 was highly expressed in a variety of tumors and that COL10A1 expression was significantly higher in pancreatic cancer than in normal tissues. The results showed that the proliferation ability of the shCOL10A1 group was significantly reduced compared to that of the Scramble group while the shCOL10A1+DDR2 group significantly reversed this . . .

     

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