Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infections

HIGHLIGHTS

  • who: Do-Hoon Lee from the (UNIVERSITY) have published the article: Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infections, in the Journal: (JOURNAL)
  • what: In the present study, a colistin-degrading enzyme was first identified from the Gram-negative opportunistic pathogen S. maltophilia, which can confer multidrug resistance and is frequently isolated with other potent Gram-negative pathogens during respiratory tract infections, such as P. aeruginosa and A. baumannii . In the present study, results from coculture and animal infection experiments showed that S. maltophilia strains producing colistin-degrading enzymes could inactivate . . .

     

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