Collagen-based biomimetic systems to study the biophysical tumour microenvironment

HIGHLIGHTS

  • who: Alessandra Cambi and Maurizio Ventre from the Department of Cell Biology, Radboud University Medical Center, Geert Grooteplein Zuid, GA Nijmegen, The Netherlands have published the article: Collagen-Based Biomimetic Systems to Study the Biophysical Tumour Microenvironment, in the Journal: Cancers 2022, 5939 of /2022/
  • what: Mainly focusing on collagen the authors compare and contrast structural and molecular complexity as well as biophysical properties of simple 2D substrates 3D fibrillar collagen gels cell-derived matrices and complex decellularized organs.
  • future: Collagen fibrils have an elastic modulus of several hundreds of MPa in the . . .

     

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