Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor

HIGHLIGHTS

• who: Sarah E. Brashear et al. from the Department of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, California have published the article: Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor, in the Journal: PLOS ONE of October/10,/2022
• what: The authors show that while BAPN was not effective at reducing collagen cross-linking the positive association between collagen cross-linking and stiffness in dystrophic muscles still show cross-linking as a viable target for reducing passive muscle stiffness . . .
  

   

  

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