Collagen type xi inhibits lung cancer-associated fibroblast functions and restrains the integrin binding site availability on collagen type i matrix

HIGHLIGHTS

  • who: Cu00e9dric Zeltz et al. from the Princess Margaret Center, University Health Network, Toronto, ON M G , Canada have published the research: Collagen Type XI Inhibits Lung Cancer-Associated Fibroblast Functions and Restrains the Integrin Binding Site Availability on Collagen Type I Matrix, in the Journal: (JOURNAL)
  • what: The authors have explored how the presence of collagen type XI in the matrix could influence CAFs` features. Unexpectedly, the authors show that collagen type XI inhibits CAF-mediated collagen remodeling and cell migration in collagen type I matrices.
  • how: The authors investigated the effect . . .

     

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