Collateral sensitivity profiling in drug-resistant escherichia coli identifies natural products suppressing cephalosporin resistance

HIGHLIGHTS

  • who: Dennis Y. Liu from the (UNIVERSITY) have published the research: Collateral sensitivity profiling in drug-resistant Escherichia coli identifies natural products suppressing cephalosporin resistance, in the Journal: (JOURNAL) of 20/01/2023
  • what: The authors report the isolation of known and new analogues of borrelidin A with potent CS activities against cephalosporin-resistant strains. The focus of this study was to explore the prevalence of CS in nature using a first-principles approach; target panel selection prioritizing diversity in drug resistance mechanisms was better aligned with this goal compared to exclusive representation by clinically . . .

     

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