Colon cancer cells secrete exosomes to promote self-proliferation by shortening mitosis duration and activation of stat3 in a hypoxic environment

HIGHLIGHTS

  • who: Ruixue Ren from the (UNIVERSITY) have published the paper: Colon cancer cells secrete exosomes to promote self-proliferation by shortening mitosis duration and activation of STAT3 in a hypoxic environment, in the Journal: (JOURNAL)
  • what: In this study the CDEs isolated from human colon cancer cell line SW480 and HCT116 showed a size range of 60-150 nm typical bilayer-encapsulated vesicles and expressed the exosomal markers CD81 and CD63.
  • how: TEM results showed that the average size of Exonormoxic (150 nm ± 5) was larger than Exo-hypoxic (60 nm ± 5). These . . .

     

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