Colony-stimulating factor-1 receptor in the polarization of macrophages: a target for turning bad to good ones?

HIGHLIGHTS

  • who: Elisabetta, Rovida and Persio Dello, Sbarba from the Department of Biomedical Sciences Experimental and Clinical "Mario Serio", Section of Pathology and Experimental Oncology, University of Florence and the Tuscan Cancer Institute, Italy have published the article: Colony-Stimulating Factor-1 Receptor in the Polarization of Macrophages: A Target for Turning Bad to Good Ones?, in the Journal: (JOURNAL)
  • how: Taken together these results indicated that pTyr-721 signaling suppresses the macrophage proinflammatory phenotype .
  • future: On the basis of the above results the authors conclude that upon CSF-1 ligation CSF-1R signaling . . .

     

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