HIGHLIGHTS
- who: Nabil N. Dagher from the All rodent experiments were performed in accordance with animal protocols approved by the Institutional Animal Care and Use Committee at the University of California, Irvine (UCI)LPS treatment: LPS (from Escherichia coli, :, have published the research: Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice, in the Journal: (JOURNAL)
- what: We find that inhibition of CSF1R alone is sufficient to eliminate microglia but the level of elimination is both dose-dependent and chronically sustainable.
SUMMARY
Neurodegenerative diseases . . .
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