Comb proteins expression levels determine helicobacter pylori competence capacity

HIGHLIGHTS

  • who: Christopher Corbinais from the Institut have published the research work: ComB proteins expression levels determine Helicobacter pylori competence capacity, in the Journal: Scientific Reports Scientific Reports
  • what: The authors show that transformation capacity is induced in strains mutated in HR genes such as addA, recO or recN, but not in the polA and mutY genes involved in other DNA repair pathways. The authors show that in H. pylori the hypermutator phenotype obtained by inactivation of MutY, a protein implicated in base excision repair35, does not increase transformation frequencies .
  • how: Consistently no orthologues . . .

     

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