HIGHLIGHTS
- who: Xiaojing Yang from the (UNIVERSITY) have published the article: Combination of radiotherapy and targeted therapy for HER2-positive breast cancer brain metastases, in the Journal: (JOURNAL)
- what: This study provides a promising novel approach for treating BCBM. The main reason is the reduction of patients with symptoms of brain metastases requiring intervention .
- how: The phase I NCT02277717 trial dose-expansion cohort enrolled 146 patients with metastatic breast cancer including 8 patients with BCBM and the results showed that SYD985 was safe and effective .
- future: Given the small number of patients . . .
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