Combination strategies to optimize the efficacy of chimeric antigen receptor t cell therapy in haematological malignancies

HIGHLIGHTS

  • who: Xinyi Xiao from the Huazhong University of Science and Technology, China have published the paper: Combination strategies to optimize the efficacy of chimeric antigen receptor t cell therapy in haematological malignancies, in the Journal: (JOURNAL)
  • future: Studies are required to determine the optimal duration of PD-1/PD-L1 inhibitor administration to avoid impairing the sustained antitumor potency of CAR T_cells.

SUMMARY

    Simultaneously, CAR T_cells are produced, and during this process pharmacological agents can be added in culture settings to produce potent T_cells for adoptive transfer. Infusion of CAR T_cells . . .

     

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