Combination tigit/pd-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer

HIGHLIGHTS

  • who: Hui Peng from the Centre Hospitalier Universitaire Vaudois (CHUV), Switzerland University of Western Australia have published the research work: Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer, in the Journal: (JOURNAL)
  • what: The experiment was repeated once and similar results were obtained. This study provides support for combination therapy using neoantigen vaccines plus immune checkpoint inhibition targeting PD-1/ TIGIT in pancreatic cancer patients. The model provides potential insights into the function the neoantigenspecific CD4 T_cells.
  • how: Flow cytometry data were analyzed using . . .

     

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