Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin)

HIGHLIGHTS

  • who: (adriamycin et al. from the Clinical Research Center, College of Medicine, Inha University have published the paper: Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin), in the Journal: (JOURNAL)
  • what: The authors demonstrate that Saos-2 tumor cells can be killed by p53-induced apoptosis, mediated with a recombinant baculovirus carrying p53 gene under the control of CMV promoter.
  • how: The results showed that BV-p53 induced cell death in a dosedependent manner for example 26 ± 2% 60 ± 1.5% and 91 ± 5% with an m . . .

     

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