Combined alteration of lamin and nuclear morphology influences the localization of the tumor-associated factor aktip

HIGHLIGHTS

• who: Mattia La Torre from the Department Biology and Biotechnology, Sapienza University, Rome, Italy have published the research: Combined alteration of lamin and nuclear morphology influences the localization of the tumor-associated factor AKTIP, in the Journal: (JOURNAL)
• what: The authors measured LMNA expression by RT-QPCR using oligos recognizing both lamin A and lamin C. This analysis shows that the levels of LMNA mRNA are significantly reduced in the three tumor cell lines (HeLa, A549, and MCF7), as compared to non-transformed cells (wild_type, HGPS and EDMD2) (Fig 4A). This analysis shows that the . . .
  

   

  

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