Combined eeg and immersive virtual reality unveil dopaminergic modulation of error monitoring in parkinson’s disease

HIGHLIGHTS

SUMMARY

    Testing PD patients under dopaminergic medication (on-condition) and after dopaminergic withdrawal (off-condition) could be an ideal model for exploring dopamine`s selective influence on different EEG error-monitoring markers. While a few EEG studies have reported reduced ERN and theta amplitude during action execution in PD patients, others reported mixed Pe and oPe results8,9. Specifically, the authors expected off-condition PD patients to show a different thetaresponse (i.e. less theta activity in response to errors) than healthy controls (HCs), while the on-condition PD patients would have a similar activity . . .

     

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