Combined treatment of marizomib and cisplatin modulates cervical cancer growth and invasion and enhances antitumor potential in vitro and in vivo

HIGHLIGHTS

  • who: Ziruizhuo Zhang from the Hokkaido University, Japan have published the article: Combined treatment of marizomib and cisplatin modulates cervical cancer growth and invasion and enhances antitumor potential in vitro and in vivo, in the Journal: (JOURNAL)
  • what: Specifically, the authors demonstrate that Mzb sensitizes cervical cancer cells to the cytotoxic effect of CDDP by upregulating Ang-1 and downregulating the expression of SCF, Flt-3L and Tie-2. The data support the model described in Figure 8.
  • how: Following the completion of CCK-8 assays the data were analyzed and combination indices . . .

     

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