Combined treatment with the phenolics (−)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces alzheimer-like pathology in mice

HIGHLIGHTS

• who: Takashi Mori from the Ethics statement All experiments were performed in accordance with the guidelines of the National Institutes of Health, and all animal studies were approved by the Saitama Medical University Institutional Animal Care and Use CommitteeAnimals were humanely cared for during all experiments, and all efforts were made to minimize suffering. Mice Male, .Cg-Tg(APPSwe, PSEN1dE9) Dbo/Mmjax mice (bearing "Swedish" APPK N/M L and , exon, deleted mutant human transgenes) on the congenic C BL/ J background (designated APP/, mice) (74) and female C BL/ J mice were obtained from The Jackson . . .
  

   

  

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