Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of lag3 and tigit improves the treatment efficacy in anti-pd1 resistant lung cancer

HIGHLIGHTS

  • who: Yun Hu from the Department of Radiation Oncology, Unit, The University of Texas MD Anderson Cancer, Holcombe Blvd, Houston, TX, USA have published the paper: Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of LAG3 and TIGIT improves the treatment efficacy in anti-PD1 resistant lung cancer, in the Journal: (JOURNAL)
  • what: This study shows a highly effective combination therapy involving nanoparticle-enhanced radiotherapy, traditional u03b1PD1, and the novel immune CPIs u03b1TIGIT and u03b1LAG3. The authors explored the possibility of increasing immune activation while reducing immune cell exhaustion through combining NBTXR3-enhanced radiation with . . .

     

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