Combining clinical and genetic data to predict response to fingolimod treatment in relapsing remitting multiple sclerosis patients: a precision medicine approach

HIGHLIGHTS

  • who: Laura Ferru00e8 and collaborators from the Neurology and Neurorehabilitation Unit, IRCCS Raffaele Hospital, Milan, Italy Raffaele University, Milan, Italy have published the research work: Combining Clinical and Genetic Data to Predict Response to Fingolimod Treatment in Relapsing Remitting Multiple Sclerosis Patients: A Precision Medicine Approach, in the Journal: (JOURNAL) of 14/Nov/2022
  • what: The authors identified a genetic signature of 123 SNPs that was able to predict FTY response with an area under the receiver operating characteristic (AUROC)=0.65 and the model accuracy further increased when considering also clinical data (AUROC=0 . . .

     

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