HIGHLIGHTS
- who: Tessa M. Popay from the (UNIVERSITY) have published the research work: Coming full circle: On the origin and evolution of the looping model for enhancer-promoter communication, in the Journal: (JOURNAL) of January/12,/2022
- what: The authors explore the emergence and development of the looping model as a means for enhancer-promoter communication and review the contrasting evidence between historical gene-specific and current global data for the role of chromatin looping in transcriptional regulation.
SUMMARY
How enhancers affect distal gene_expression has been a major question in the field . . .
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