Commensal gut bacteria modulate phosphorylation-dependent pparγ transcriptional activity in human intestinal epithelial cells

HIGHLIGHTS

• who: Malgorzata Nepelska from the (UNIVERSITY) have published the Article: Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells, in the Journal: (JOURNAL) of 07/03/2017
• what: The authors aimed to identify commensal gut bacteria able to regulate this crucial nuclear receptor using commensal bacterial cultures and PPARγ​-dependent reporter cells. In that study, cells were directly exposed to the living bacteria, while the approach focused on secreted bioactive molecules since only CMs were tested. The experiments showed that A. parvulum and P. copri can affect the phosphorylation status . . .
  

   

  

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