Common genetic variants associated with parkinson’s disease display widespread signature of epigenetic plasticity

HIGHLIGHTS

  • who: Common genetic variants and collaborators from the DepartmentUniversity Clinic, Osaka, Japan have published the Article: Common genetic variants associated with Parkinson’s disease display widespread signature of epigenetic plasticity, in the Journal: Scientific Reports Scientific Reports of 20/Nov/2019
  • what: As nucleosome positioning varies in different cell types, in the analysis the authors show only the SNPs with significant read distribution (P ≤ 0.05) in every cell type. The authors focused on the PD associated SNPs embedded within SNCA gene and investigated their epigenetic landscape. The authors propose that the sequence specific recognition . . .

     

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