HIGHLIGHTS
- who: Du00e9siru00e9e Tampe from the Department of Nephrology and Rheumatology, University Medical Center Gu00f6ttingen, Gu00f6ttingen, Germany have published the article: Comparative analysis of complement C3 and C4 serum levels for outcome prediction in ANCA-associated renal vasculitis, in the Journal: (JOURNAL)
SUMMARY
The activation of the complement system contributes essentially to the pathogenesis of ANCA-associated renal vasculitis by autoantibody-antigen recognition directed against host cells. The measurement of serum complement C3 and C4 with immunoassays is routinely used in clinical practice to determine and monitor complement activation. Low serum complement C3 levels . . .
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