Comparative analysis of gene ontology-based semantic similarity measurements for the application of identifying essential proteins

HIGHLIGHTS

  • who: Xiaoli Xue et al. from the School of Science, East China Jiaotong University, Nanchang, China, School of Computer and have published the Article: Comparative analysis of gene ontology-based semantic similarity measurements for the application of identifying essential proteins, in the Journal: PLOS ONE of 28/03/2023
  • what: The authors propose a novel strategy to identify key proteins by constructing reliable PPI networks. The authors compare the numbers of key proteins identified properly and the prediction precisions under different types of strategies.
  • how: Six centrality methods (the BC DC EC NC . . .

     

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