Comparative analysis of posiphen pharmacokinetics across different species—similar absorption and metabolism in mouse, rat, dog and human

HIGHLIGHTS

  • What: The following PK parameters were collected for the purpose of this manuscript: maximum concentration (Cmax), time to maximum drug concentration (Tmax), half-life (T1/2), and the Area Under the Curve (AUC). Due to the low number of human subjects (n=4), the study was not 4 of 12 sufficiently powered to perform statistical analysis and, hence, only mean values for Cmax are presented.
  • Who: Maria L. Maccecchini and Diane R. Mould from the Inc, Lindenwood, Malvern, PA, USA have published the research: Comparative Analysis of Posiphen Pharmacokinetics across Different Species—Similar Absorption and . . .

     

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