Comparative chiral separation of thalidomide class of drugs using polysaccharide-type stationary phases with emphasis on elution order and hysteresis in polar organic mode

HIGHLIGHTS

  • who: Mohammadhassan Foroughbakhshfasaei and colleagues from the Department of Pharmaceutical Chemistry, Semmelweis University, Hou030bgyes EStr9, Budapest have published the article: Comparative Chiral Separation of Thalidomide Class of Drugs Using Polysaccharide-Type Stationary Phases with Emphasis on Elution Order and Hysteresis in Polar Organic Mode, in the Journal: Molecules 2022, x of 23/Nov/2021
  • what: The study reports several cases of EEO reversal, depending on various characteristics of the chiral selectors and the composition of the mobile phase.

SUMMARY

    In contrast the immunomodulatory drugs (IMIDs) (THAL, POM and LEN) are marketed . . .

     

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