Comparative effects of chloride channel inhibitors on lrrc8/vrac-mediated chloride conductance

HIGHLIGHTS

  • who: Christophe Duranton from the Université Montpellier, Montpellier, France University of Poitiers, France have published the article: Comparative Effects of Chloride Channel Inhibitors on LRRC8/VRAC-Mediated Chloride Conductance, in the Journal: (JOURNAL)
  • what: The authors explored the efficacy of six commonly used chloride channel inhibitors on VRAC/LRRC8 conductance using the patch-clamp technique and characterized their actions on the VRAC-related volume regulatory function. The authors evaluated the effects of three known CFTR inhibitors on VRAC conductance in cells lacking CFTR. The authors report here in the HEK-293 cell line devoid of . . .

     

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