HIGHLIGHTS
- What: This systematic review aimed to evaluate existing comparative studies regarding the impact of semaglutide compared to another GLP-1 RA (liraglutide and efinopegdutide) in facilitating weight reduction and safety profile in patients with obesity . The aim of this comprehensive analysis is to provide insights for clinicians and patients when selecting a GLP-1 RA, as well as to identify gaps in the current literature that can be explored further to optimize patient outcomes and quality of life. Four studies compared semaglutide against liraglutide in affecting weight loss, and three demonstrated semaglutide`s significant effect in facilitating . . .

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