Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of mapk/erk targets in embryonic kidney

HIGHLIGHTS

  • who: Kristen Kurtzeborn from the University of Helsinki, Helsinki, Finland have published the article: Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney, in the Journal: (JOURNAL)
  • what: Using tissue-specific MAPK/ERK inactivation and RNA sequencing in combination with experimentau2011 tion in embryonic kidneys the authors demonstrate here that MAPK/ERK signaling maintains ureteric bud tip cells suggesting u2020 and are co-first authors. MAPK/ERK activation in the ureteric bud is required to maintain tip cell identity Next, the authors focused on . . .

     

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