Comparing biparametric to multiparametric mri in the diagnosis of clinically significant prostate cancer in biopsy- naive men (prime): a prospective, international, multicentre, non- inferiority within- patient, diagnostic yield trial protocol

HIGHLIGHTS

• who: Aqua Asif u200d u200d and collaborators from the University College London have published the research work: Comparing biparametric to multiparametric MRI in the diagnosis of clinically significant prostate cancer in biopsy- naive men (PRIME): a prospective, international, multicentre, non- inferiority within- patient, diagnostic yield trial protocol, in the Journal: BMJ Open 2023;13:e070280. of 24/08/2020
• what: A paired cohort design was chosen rather than a randomised trial design for the following reasons: More efficient design (sevenfold lower sample size required) with equivalent quality of evidence in the setting of a diagnostic . . .
  

   

  

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