HIGHLIGHTS
SUMMARY
Evidence of waning vaccine immunity over time has emerged: following the second vaccine, there is a significant drop in effectiveness against symptomatic infection; from a peak of ~90% in the weeks immediately following vaccination to a much lower 50-80% 6 months after vaccination2-6. As public health officials face the challenges of continuing waves of infection, it is critical to understand how vaccineinduced immunity (with and without a booster vaccine) compares with infection-induced immunity (with and without an enhancer vaccine) in preventing COVID-19-related hospitalization. The number of person-days contributed . . .
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