Comparison between intratumoral and intravenously administered oncolytic virus therapy with newcastle disease virus in a xenograft murine model for pancreatic adenocarcinoma

HIGHLIGHTS

• who: J. Fru00e9derique de Graaf from the Viroscience Department, Erasmus Medical Centrum, Rotterdam, the Netherlands have published the article: Comparison between intratumoral and intravenously administered oncolytic virus therapy with Newcastle disease virus in a xenograft murine model for pancreatic adenocarcinoma, in the Journal: (JOURNAL)
• what: The authors aimed to address the question whether IT or IV injections lead to systemic viral distribution. Altogether, the study demonstrates that IV injections with NDV F3aa results in anti-tumor efficacy in an immune deficient subcutaneous murine model, within 10 days of treatment, and suggest this administration route is . . .
  

   

  

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