Comparison of absorbed dose extrapolation methods for mouse-to-human translation of radiolabelled macromolecules

HIGHLIGHTS

  • who: Francesco Cicone from the University of Lausanne, Lausanne, Switzerland have published the research: Comparison of absorbed dose extrapolation methods for mouse-to-human translation of radiolabelled macromolecules, in the Journal: (JOURNAL)
  • what: The aim of this study was twofold. For the purpose of the present study, source organ TIACs obtained in patients were used as input in OLINDA/EXM v.2.1. In an effort to contribute to the standardization of translational dosimetry, in this article the authors focused on the computational aspects of mouse-to-human AD extrapolations. The second objective of the . . .

     

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