Comparison of alitretinoin with puva as the first- line treatment in patients with severe chronic hand eczema (alpha): study protocol for a randomised controlled trial

HIGHLIGHTS

• who: Isabelle L Smith and colleagues from the Committees who have provided input into the patient information sheet and other trial documentationBoth PPI representatives also provide input into the design and conduct of the trial to ensure the patient perspective is fully integrated in key decisions about the trial, delivery and interpretation/ dissemination of findings. Ethics and dissemination The trial was reviewed and approved by the Yorkshire and Humber Research Ethics Committee (REC reference:, YH/1259), the Health Research Authority (HRA) and Medicine and Healthcare products Regulatory Agency (MHRA). Sites will be informed of any and all . . .
  

   

  

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