HIGHLIGHTS
- who: Ritu M. Ramamurthy and collaborators from the Mercer University, United States have published the research work: Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII, in the Journal: (JOURNAL)
- what: The aim of this study was to investigate whether CRISPR/Cas9 can be used to achieve locationspecific insertion of a fVIII transgene into a genomic safe harbor, thereby eliminating the potential risks arising from the semi-random genomic integration inherent to lentiviral_vectors. With each cell type, the authors compare the success and efficiency of the CRISPR/Cas9 . . .
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