Comparison of dna targeting crispr editors in human cells

HIGHLIGHTS

  • who: Hongxin Huang from the Cancer Research Institute, School of Basic Medical Sciences, Medical University, Guangzhou, China have published the Article: Comparison of DNA targeting CRISPR editors in human cells, in the Journal: (JOURNAL)
  • what: The authors made a parallel comparison between the recently reported miniature Cas12f1 (Un1Cas12f1 and AsCas12f1) and the widely used Cas12a and Cas9 nucleases in mammalian cells. The authors intended to examine the editing activities of these six DNA editors, because the editing efficiency was a key concern for a CRISPR-Cas gene-editing tool. In contrast, for the experiments related . . .

     

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