Comparison of fixed cell-based assay to radioimmunoprecipitation assay for acetylcholine receptor antibody detection in myasthenia gravis

HIGHLIGHTS

  • who: Ario Mirian et al. from the Western University Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada have published the research work: Comparison of fixed cell-based assay to radioimmunoprecipitation assay for acetylcholine receptor antibody detection in myasthenia gravis, in the Journal: (JOURNAL)

SUMMARY

    Myasthenia gravis (MG) is an antibody-mediated neuromuscular junction disorder characterized by abnormal muscle fatigability that may selectively affect ocular muscles or be more generalized. Approximately 50% of ocular and 85% of generalized MG patients are anti-AChR-positive by radio­ immunoprecipitation assay . . .

     

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