HIGHLIGHTS
- who: Sumiko Ohnami from the Center Research Institute have published the paper: Comparison of genetic susceptibility to lung adenocarcinoma and squamous cell carcinoma in Japanese patients using a novel panel for cancer-related drug-metabolizing enzyme genes, in the Journal: Scientific Reports Scientific Reports
- what: In the present study, the ALDH2 (rs568781254) or DPYD variants (rs190771411 and rs200562975) were associated with an increased risk of squamous cell carcinoma patients compared to adenocarcinoma. The rs200562975of DPYD identified in this study reportedly reduced enzymatic activity to less than 70% of wild-type in_vitro21. The aim of this . . .
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