Compartmentalized synthesis of triacylglycerol at the inner nuclear membrane regulates nuclear organization

HIGHLIGHTS

• who: Antonio D. Barbosa from the Institut University of Cambridge, Cambridge , XY, UK have published the article: Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization, in the Journal: (JOURNAL) of September/23,/2019
• what: The authors show that Lro1 an acyltransferase that generates TGs from phospholipid-derived FAs yeast relocates from the endoplasmic reticulum to a subdomain of the inner nuclear membrane. The authors focused on mutants with defects in Lro1 targeting during the PDS phase (and hence displaying increased ER localization compared to the wild-type) or decreased overall Lro1 . . .
  

   

  

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