Competitive elisa for a serologic test to detect dengue serotype-specific anti-ns1 iggs using high-affinity ub-dna aptamers

HIGHLIGHTS

• who: Ken-ichiro Matsunaga from the InstitutTechnological University have published the article: Competitive ELISA for a serologic test to detect dengue serotype-specific anti-NS1 IgGs using high-affinity UB-DNA aptamers, in the Journal: Scientific Reports Scientific Reports of 16/04/2021
• what: During the study, the authors serendipitously found that the UB-DNA aptamer binding to DEN-NS1 is serotype-specifically inhibited when anti-DEN-NS1 IgG antibodies were present in patient blood samples.
• how: Since the Px nucleoside is unstable and thus not suitable for chemical DNA synthesis instead of . . .
  

   

  

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