HIGHLIGHTS
- who: Lu Du from the (UNIVERSITY) have published the paper: Complement C3 deficiency alleviates alkylation-induced retinal degeneration in mice, in the Journal: (JOURNAL)
- what: C3 deficiency preserves retinal function Since the authors found an increase in the production of C3 in the MMS-treated mouse retina, the authors aimed to elucidate the function of C3 using the MMS-induced retinal degeneration model.
- how: It was found that alkylation-induced retinal degeneration is sex dependent and that male animals are more sensitive to MMS so the authors chose to work with male mice . . .
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