Complement-dependent cytotoxicity of human autoantibodies against myelin oligodendrocyte glycoprotein

HIGHLIGHTS

  • who: Kuniko Kohyama from the United Kingdom University of Innsbruck, Austria have published the article: Complement-dependent cytotoxicity of human autoantibodies against myelin oligodendrocyte glycoprotein, in the Journal: (JOURNAL)
  • what: In the experiment for IgG subclass assessment, phycoerythrin (PE)-labeled anti-human IgG 1, 2, 3, or 4 (Abcam Japan, Tokyo) was used as a second antibody.
  • how: The same examinations are performed three times and the mean data is shown. The authors showed that antibody-mediated cell damage depended on complement because heat-inactivated sera lost cytotoxic activity.
  • future: The . . .

     

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