HIGHLIGHTS
- who: Neeltina M. Jager from the United States University of Bern, Switzerland have published the Article: Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys, in the Journal: (JOURNAL)
- what: As part of the PROPER trial, this study investigated the role of complement activation during NMP in human discarded kidneys. This study shows that complement activation is strongly correlated with the release of the proinflammatory cytokines IL-6, IL-8, and TNF. The authors demonstrated that the significant increase in sC5b-9 perfusate levels result in a significant lower creatinine Frontiers . . .
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