Complement lectin pathway activation is associated with covid-19 disease severity, independent of mbl2 genotype subgroups

HIGHLIGHTS

  • who: Lisa Hurler and colleagues from the University of Gdanu0301sk, Poland, Medical have published the research: Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups, in the Journal: (JOURNAL)
  • what: The authors show that the lectin pathway is activated in acute COVID-19, indicated by the correlation between complement activation product levels of the MASP-1/C1-INH complex (p=0.0011) and C4d (p and amp;lt;0.0001) and COVID-19 severity. The study showed associations of both cytokine levels and complement components with follow-up . . .

     

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